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Are you aware of the effects smoking has on your liver?

Smoking has a number of negative consequences on organs that do not come into direct touch with the smoke, such as the liver. It has three key negative effects on the liver : direct or indirect toxicity, immunological effects, and carcinogenic consequences. Tobacco use produces chemical compounds with cytotoxic potential, which contribute to necroinflammation and fibrosis. Furthermore, smoking promotes the production of pro-inflammatory cytokines (IL-1, IL-6, and TNF-), which are implicated in liver cell damage. It promotes secondary polycythemia and, as a result, increased red cell mass and turnover, which may be a contributing factor to secondary iron overload illness by boosting oxidative stress in hepatocytes. Increased red cell mass and turnover are linked to increased purine catabolism, which promotes excessive uric acid generation. Smoking impairs both cell-mediated and humoral immune responses by inhibiting lymphocyte growth and promoting lymphocyte death. Smoking also raises
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Is it true that coffee is terrible for your liver?

The enzymes generated by the liver to break down coffee also aid in the breakdown of pregnancy hormones. Women have more of these enzymes in their liver than males, so they can metabolise caffeine faster. Because the enzymes are busy metabolising pregnancy hormones during pregnancy , the time it takes for caffeine to be metabolised increases. This can have a detrimental influence on a pregnant woman's overall health. Caffeine use can help those who are at risk of developing chronic liver disease, as well as those who have obesity, iron overload, hepatitis B or C, or who consume a lot of alcohol. According to a research, those who consume a little amount of caffeine-containing beverages had a lower chance of getting chronic liverdisease than those who consume more caffeine-containing beverages. Caffeine breaks up fat accumulated in liver cells, which may be advantageous to individuals with liver disease, according to researchers who conducted comprehensive study. Caffeine use

Do you know what are the most common signs & symptoms of gastrointestinal disorders?

We all have digestion issues from time to time. So how are you expected to tell when your GI symptoms are just a little annoyance and when they're a sign of a serious digestive problem? When they're severe and/or persistent. The severity of gastrointestinal symptoms can range from minor to severe. If you're having the symptoms listed below on a regular basis or they're causing you a lot of pain, your body may be attempting to notify you that you have a digestive problem. Excess Gas & Bloating Bloating can be caused by GI issues such as Irritable Bowel Syndrome (IBS) or food intolerances like Celiac disease. Constipation Constipation is defined by the National Institutes of Health (NIH) as having fewer than three bowel motions per week or passing firm, dry stool. Constipation is a warning indication for a number of digestive illnesses, including IBS with constipation. If constipation is a regular occurrence in your life, you may have chronic constipation,

What are the effects of gastrointestinal disorders on your teeth?

According to the American Nutrition Association , 70 million Americans have digestive problems such as acid reflux (heartburn), constipation and irritable bowel syndrome. Every time you bite into food, you are reminded that your mouth is connected to your stomach. However, did you know that the health of your mouth can affect your gastrointestinal system? These factors can have an impact on your oral health. You can learn more about how a dentist may be able to help by reading on. Digestive issues are influenced by oral health Digestive health depends on the ability to chew, and chewing depends on healthy teeth and gums. When your teeth are misaligned or missing-or, when gum disease makes chewing painful, may not be able to chew food properly. This can lead to digestive issues. In addition, gum disease indicates that bacteria are likely traveling through your digestive tract with your food and saliva. You may also experience digestive imbalances as a result of this. Digestion Disorde

What Are the Most Common Causes of Diverticulosis?

Diverticulosis: Diverticulosis occurs when small pouches called diverticula form in the wall of the large intestine (colon) and push through weak parts of the outer muscular layers in the colon. Consequences of Diverticulosis Diverticulosis, in the vast majority of cases, is asymptomatic . However, a person with diverticulosis may experience the following symptoms: - Bloating, bloating, and diarrhea - Cramping or pain in the lower abdomen. Consult a doctor if you have symptoms of diverticular bleeding, such as blood in your stool that is mostly red or maroon in color, Dizziness, Lightheadedness, Weakness. The inflamed diverticula result in diverticulitis, which produces symptoms of discomfort, nausea, vomiting, diarrhea, fever, constipation, and diarrhea. Causes of Diverticulosis Western countries generally have a low-fiber diet that leads to diverticulosis. However, diverticulosis can also be caused by the following factors: Constipation makes you strain to pass stool. Genetics Obes

Primary biliary cirrhosis (PBC): Causes, Signs, Symptoms and Treatment

  Primary biliary cirrhosis (PBC) is a progressive liver disease characterized by bile accumulation (cholestasis) that causes damage to the small bile ducts that drain bile from the liver. This pressure buildup eventually damages the bile ducts, causing liver cell destruction. Cirrhosis and liver failure develop as the disease advances and enough liver cells die. Bile is produced in the liver and then delivered via the bile ducts to the gallbladder and gut, where it aids in the digestion of fats and fat-soluble vitamins (A,D,E,K). When bile is unable to be emptied from the liver, it causes inflammation and cell death. Scar tissue progressively replaces the areas of the damaged liver, and the body is unable to execute essential processes. Causes of primary biliary cirrhosis PBC has an unclear cause. It is most likely an autoimmune disease, in which the immune system assaults the body's own cells. The bile ducts are attacked and damaged in this condition. Risk factors for prim